'Understanding the genotype-phenotype map and its practical implications' by Prof Stig Omholt, Research Professor at the Norwegian University of Science and Technology (NTNU) in Trondheim and at the Norwegian University of Life Sciences (UMB) at Aas, Norway.
Key points
The relation between genotype and phenotype can be conceptualized as a genotype-phenotype map (GP map), assigning a phenotype to each possible genotype. The GP map concept applies to any time point in the ontogeny of a living system and it is an abstraction of a relation that is the outcome of very complex dynamics that include environmental effects. An understanding of this dynamics has the potential to become transformative also for the aquaculture sector. However, it demands introduction of methodology and concepts that go far beyond what is contained in current genome- mapping paradigms. The talk will focus on the challenges involved in filling the genotype-phenotype gap with causal content and point to possible practical implications.
About
He was until recently Director of the Centre for Integrative Genetics (CIGRENE) at UMB and Kristine Bonnevie professor at the COE Centre for Ecological and Evolutionary Synthesis at the University of Oslo. He is now Director of a newly established cross-campus biotechnology programme at NTNU, named NTNU Biotechnology - the Confluence of Life Sciences, Mathematical Sciences and Engineering.
Stig Omholt has over the years worked on a wide range of research themes, including sociobiology, biogerontology, mathematical modelling of brain physiology, the mathematics of tanning, linking genetics theory with systems dynamics to establish a real quantitative genetics theory, experimental evolution of single-celled eukaryotes, linking genetics to cardiovascular modelling, the etiology of hypertension, and the ultimate reasons for why the salmon possesses a pink flesh. Omholt played a key role in the establishment as well as the funding of the Atlantic Salmon Genome Sequencing Project. He was also involved in the sequencing of the Atlantic cod genome.
More information...
Key points
The relation between genotype and phenotype can be conceptualized as a genotype-phenotype map (GP map), assigning a phenotype to each possible genotype. The GP map concept applies to any time point in the ontogeny of a living system and it is an abstraction of a relation that is the outcome of very complex dynamics that include environmental effects. An understanding of this dynamics has the potential to become transformative also for the aquaculture sector. However, it demands introduction of methodology and concepts that go far beyond what is contained in current genome- mapping paradigms. The talk will focus on the challenges involved in filling the genotype-phenotype gap with causal content and point to possible practical implications.
About
He was until recently Director of the Centre for Integrative Genetics (CIGRENE) at UMB and Kristine Bonnevie professor at the COE Centre for Ecological and Evolutionary Synthesis at the University of Oslo. He is now Director of a newly established cross-campus biotechnology programme at NTNU, named NTNU Biotechnology - the Confluence of Life Sciences, Mathematical Sciences and Engineering.
Stig Omholt has over the years worked on a wide range of research themes, including sociobiology, biogerontology, mathematical modelling of brain physiology, the mathematics of tanning, linking genetics theory with systems dynamics to establish a real quantitative genetics theory, experimental evolution of single-celled eukaryotes, linking genetics to cardiovascular modelling, the etiology of hypertension, and the ultimate reasons for why the salmon possesses a pink flesh. Omholt played a key role in the establishment as well as the funding of the Atlantic Salmon Genome Sequencing Project. He was also involved in the sequencing of the Atlantic cod genome.
More information...
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| Stig Omholt |
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